DNA Testing

DNA LIFE®
GIVE YOUR BODY EXACTLY WHAT IT NEEDS
WHERE IT NEEDS IT

Every cell in the human body contains “Genes” that determine all our physical, emotional and intellectual traits and in fact greatly influence our health and physical fitness as well our predisposition to disease and response to medication. These genes are made up of DNA (deoxyribonucleic acid) and are the template to make proteins in our body. We inherit our genes from our parents and pass them onto our children.

The interesting thing about Human DNA is that 99% of its constituents are identical between individuals and only the remaining 1% are unique. This unique one percent contains small variations known as SNPs (single nucleo- tide polymorphisms) and these little variations make each one of us the distinct person we are.

INTRODUCING DNA LIFE

WHY DNA LIFE?

DNA Life is one the specialized tests that study these SNPs and therefore provide crucial insights into our genetic makeup and ultimately into our body’s functioning. This in turn helps health professionals and fitness coaches make informed choices based on which treatments, supplements, therapies and regimes an individual would respond most positively to. Also, it helps trace the roots of and determine the genetic basis of various physical, psychologi- cal and behavioural conditions. Ultimately all of this holds the key to providing individualised healthcare to people in a manner that is specially tailored to them from their diet to their medicine and even exercise. This is why DNA Life holds the key to the future of healthcare and is a must for any serious contender in the field.

HOW DOES DNA LIFE WORK?

DNA Life® is dedicated to providing healthcare practitioners with training and education to accurately interpret genetic test results. Our cutting edge genetic tests (DNA Diet, DNA Health, DNA Sport, DNA Oestrogen) provide valuable information across the health spectrum; from weight management and risk of chronic diseases, to optimal training and recovery strategies.

Every person responds and reacts to different foods differently and your genetic makeup is the reason behind it. Genetic testing and Nutrigenomics are the future of individualised healthcare. Although reliable genetic testing is readily available for clinical use, genetics is still a relatively new clinical tool. Until recently, healthcare practitioners have been left to educate themselves in this exciting area of clinical science, by simply picking up information where they can. It is for this reason that Nordic Laboratories and DNAlysis Biotech- nology, both promoters of individualized medicine, created DNA Life®.

WHY ARE SNPS IMPORTANT?

We know that a SNP is a variation in a single nucleotide that occurs at a specific position in the genome. Although, SNPs alone will not cause disease, however they can predict which diseases an individual is prone to have and change responsiveness to environmental factors.

GENETIC TESTING AND WHY IT’S SO IMPORTANT

Genetic testing is a type of medical test that involves the detection of specific alleles, mutations, genotypes or karyotypes that are associated with heritable traits, diseases or predispositions to disease for the individual or their descendants. It identifies changes in chromosomes, genes or proteins by getting to the basis of a patient’s biochemistry. The results of a genetic test can confirm or rule out a suspected genetic condition.

NUTRIGENOMIC TESTING AND PHYSICAL FITNESS

Nutrigenomics testing helps in identifying and evaluating certain genetic markers and develop a comprehensive report along with recommendations that help a person in achieving the fitness level they desire with determining a patient’s unique metabolic needs. We usually take supplements in hopes of improving our nutrition, but we lack the specific knowledge or a scientific basis for our nutritional needs, and therefore end up wasting money on supplements with little to no benefit. Personalised genetic testing solves this problem by providing patients with a targeted, concrete, evidence-based account of their specific nutritional needs. Nutrigenomic services are totally safe and completely non-invasive, requiring only a cheek swab or saliva for a functional sample.

Types of tests available

A number of tests are available in this range include the following:

Price: £350 | Duration: 1 hour (including consultation)

DNA HEALTH AND THE VALUE OF

GENETIC TESTING

DNA Health tests investigate SNPs that provide information about genetic variations, which are frequently seen in the population (> 5%). SNPs can have a profound effect on the functioning of the genes in which they are found. This in turn affects the biological pathway in which the gene is active, affecting metabolic functions that are important for maintaining a state of health.

It is highly unlikely that this form of genetic testing will lead to findings of serious genetic diseases, but the knowledge of a patient’s SNPs offers a powerful health advantage, enabling the trained healthcare practitioner to prescribe precise lifestyle and nutritional recommendations (Nutrigenomics) aimed at compensating for the genetic variants.

TEST PROCEDURE

The laboratory analyses a patient’s DNA using a process called Polymerase Chain Reaction (PCR), which amplifies tiny quantities of DNA to detectable levels, before looking for specific genetic variations, or ‘SNPs’, in the DNA.

CLINICAL VALUE

  • Highlights specific metabolic pathways that may require extra support
  • Provides recommendations that involve optimisation of quantities of certain nutrients, vitamins and minerals
  • Suggests whether an individual is better able to reduce their cholesterol levels through diet, as opposed to through medication
  • Provides an indication of the degree of susceptibility to the harmful effects of carcinogens ingested in the diet

DNA HEALTH TEST REPORT CONTENTS

The report provides:

  • The level of impact of any genetic variants identified
  • An explanation of their impact on health
  • Appropriate nutritional and lifestyle recommendations

The results are divided in sections of key metabolic function, so that genetic weaknesses and strengths within a functional area can be easily identified.

TEST RESULTS

The results are presented in a report, which provides a list of all the genes tested and describes their impact on the relevant metabolic or biochemical process.

Some gene variations are advantageous, while others may contribute to increased health risks. Their level of influence is indicated in the test report using a gene impact scale.

DNA Health test reports on genes involved in the following metabolic areas:

• Lipid metabolism • Bone health
• Methylation • Inflammation

The DNA Health test is designed to optimise well-being and health by personalising lifestyle and diet choices and, where necessary, using supple- ments tailored to offset any particular nutritional deficit based on specific gene variants. The DNA Health approach assists the healthcare practitioner in establishing the optimal nutrition necessary for good health, longevity and disease risk mitigation.

Diet is a key factor in determining genomic stability as it impacts on all relevant pathways: exposure to dietary carcinogens, biotransformation, DNA repair and synthesis, and apoptosis. Current recommend- ed dietary allowances for vitamins and minerals are based largely on the prevention of diseases or deficiency.

However, because diseases of lifestyle are partly caused by damage to DNA it stands to reason that we should focus our attention on defining optimal requirements of key minerals and vitamins for preventing genomic instability. Additional attention should be paid to individuals with genetic polymor- phisms that alter the bioavailability of specific micro-nutrients and the affinity of specific key enzymes for their micro-nutrient co-factor.

Price: £350 | Duration: 1 hour (including consultation)

DNA DIET AND ITS

WONDERS

Although it might have been seen as unimaginable, now creating a fool proof diet to achieve an individual’s health goals in within reach. DNA Diet includes well-researched gene variations that impact weight management. 40–80% of the variance in body weight is due to genetic factors, which is why not everyone gains or loses weight while following the same diet, despite being exposed to similar environments. Identifying an individual’s responsiveness to diet and lifestyle modification to control weight can be extremely advantageous.

DNA DIET REPORTS ON THE FOLLOWING AREAS:

  • Variations linked to obesity and being overweight
  • Ability to lose or gain weight easily
  • Responsiveness to exercise
  • Mobilisation of fat from fat cells
  • Ability to metabolise fats for energy
  • Metabolic rate
  • Absorption rate of dietary fat

DNA DIET TEST REPORT CONTENTS

The Diet report provides:

  • The level of impact of any genetic variants identified
  • An explanation of their impact on weight management
  • Appropriate nutritional and lifestyle recommendations. This includes:
    • Weight management priorities
    • Diet plan principles
    • Exercise planning and how to calculate MET hours

CLINICAL VALUE

  • Provides strategies for weight management based on genetic make-up
  • Provides motivation to individuals with a goal to lose weight
  • Provides an understanding of why previous weight management programmes may have been unsuccessful
  • Provides insight to which diet type (i.e. Mediterranean style, low carbohydrate, and low fat diet) may be most suited to an individual to manage weight, based on genotype

Price: £350 | Duration: 1 hour (including consultation)

DNA OESTROGEN

It is worth mentioning that the DNA Oestrogen Test is particularly life saving and is a major development in the field. Consider for instance how approximately 80% of times breast cancer occurs in women with no family history. Oestrogen affects the function of a number of target tissues and research has shown that an increased lifetime exposure to Oestrogen is a strong risk factor in the development of breast cancer. DNA Oestrogen tests for gene variants that have been shown to have an impact on how Oestrogen is metabolised. Guiding the personalisation of diet, hormone and nutritional supplement recommendations, based on the insight gained from the DNA Oestrogen test, to improve oestrogen metabolism is of benefit to men and women who suffer from numerous oestrogen-dominant conditions and who have higher lifetime exposure to oestrogens, oestrogen metabolites and other carcinogens

DNA OESTROGEN REPORTS ON THE FOLLOWING AREAS:

  • Polymorphisms in key genes involved in metabolising oestrogen and related compounds
  • Impact of high-risk polymorphisms
  • Intervention strategies for carriers
  • Personal risk factors associated with HRT, Oral contraceptives, bio-identical supplementation and in-vitro fertilisation

DNA OESTROGEN TEST REPORT CONTENTS

The report provides:

  • The level of impact of any genetic variants identified
  • An explanation of their impact on oestrogen metabolism
  • Appropriate nutritional and lifestyle recommendations to support healthy oestrogen metabolism

CLINICAL VALUE

These tests are recommended for:

  • Men or women with a strong family history of breast, ovarian, colon or prostate cancer
  • Women who suffer from oestrogen-dominant conditions such as endometriosis, premenstrual syndrome and uterine fibroid tumours
  • Women considering oral contraceptives, hormone replacement therapy or bio-identical hormone supplementation
  • Women who are considering in vitro fertilization or who have been diagnosed with oestrogen receptor-positive breast cancer

Price: £350 | Duration: 1 hour (including consultation)

DNA SPORT

DNA Sport examines various biological areas that impact training responsiveness and sporting performance. These include soft tissue and bone formation and remodeling; inflammation; oxidative stress; oxygenation influenced by blood flow and respiration; energy and fuel production; and metabolism during exercise.

Knowledge of gene variations that influence these key biological areas can be used to exploit any genetic advantages and identify any weaknesses that need to be supported, through diet and the training strategies.

DNA SPORT REPORTS ON THE FOLLOWING AREAS:

  • Circulation and blood pressure
  • Strength
  • Cardio-pulmonary capacity
  • Muscle fibre specialisation and hypertrophy
  • Cardiac input
  • Muscle metabolism
  • Adaptability to training regimes
  • Structural integrity of soft tissues
  • Inflammation and free radical stress

CLINICAL VALUE

Suitable for the recreational athlete and the elite performance athlete, it provides information to optimise:

  • Power and endurance – physiological factors
  • Structural integrity – tendon pathology and injury risk
  • Recovery – training patterns and nutrition

DNA SPORT TEST REPORT CONTENTS

The report provides:

  • The level of impact of any genetic variants identified
  • An explanation of their impact on sport performance, injury and recovery risk
  • Appropriate nutritional and lifestyle recommendations in relation to health and sports performance, including:
    • Power and endurance
    • Athletic potential and key training principles
    • Injury and recovery

Price: £350 | Duration: 1 hour (including consultation)

DNA SKIN

GENETIC TESTING

There are lots of skin care products available, but a cream or treatment that works well for someone else might not be the right one for you. It is important to understand exactly how your skin responds to environmental factors such as sun exposure and which specific skin care ingredients are best suited to your skin profile. A skin care DNA test can shed new light on your skin’s exact needs.

CLINICAL VALUE

DNA Skin test identifies your skin’s genetic potential in seven key areas:

● Collagen quality ● Skin elasticity
● Fine lines and wrinkles ● Sun protection
● Pigmentation ● Skin antioxidants
● Skin sensitivity

DURATION OF TIME REQUIRED

The usual time required to get the to get the result of a DNA test is 4-6 weeks.

Get all 5 tests for only £1550